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. 2021 Nov 13;13(22):5683. doi: 10.3390/cancers13225683

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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(a) CLIN plan with manually selected beam angles for patient 1. (b–d) iCE plans with 6, 4 and 8 optimized beam angles for the same patient. Dose is shown relative to the prescribed dose (66 Gy). Contours are the PTV (red), lungs (yellow), heart (magenta), esophagus (grey) and spinal cord (cyan), and beam angles are indicated by white lines.