Table 5.
Dose-volume metrics for CLIN compared with iCE and iCE_noBAO plans. Median value and interquartile range (IQR) is given, along with p-values for difference with regard to CLIN. Significant differences from CLIN are marked with *.
| Dose Metric | CLIN | iCE | iCE_noBAO | |||||
|---|---|---|---|---|---|---|---|---|
| Median | IQR | Median | IQR | p | Median | IQR | p | |
| PTV V95% [%] | 99.0 | 0.9 | 99.2 | 0.5 | 0.1 | 99.3 | 0.5 | 0.2 |
| Lungs Dmean [Gy] | 14.7 | 4.2 | 14.2 | 4.7 | 0.3 | 14.6 | 4.4 | 0.4 |
| Lungs V5Gy [%] | 55.8 | 11.7 | 54.7 | 10.9 | 0.6 | 57.4 | 12.7 | 0.1 |
| Lungs V20Gy [%] | 25.0 | 6.7 | 24.4 | 7.9 | 0.5 | 24.3 | 7.0 | 0.2 |
| Heart Dmean [Gy] | 9.0 | 7.1 | 8.1 | 5.9 | 0.02 * | 8.3 | 6.7 | 0.07 |
| Heart V5Gy [%] | 34.0 | 33.1 | 31.8 | 30.9 | 0.7 | 33.2 | 31.6 | 0.9 |
| Heart V30Gy [%] | 11.0 | 9.5 | 6.2 | 6.5 | 0.002 * | 8.8 | 8.4 | 0.002 * |
| Esophagus Dmean [Gy] | 20.3 | 8.2 | 18.5 | 9.2 | 0.02 * | 18.9 | 9.1 | 0.05 * |
| Esophagus V20Gy [%] | 38.4 | 14.3 | 36.8 | 17.7 | 0.008 * | 35.4 | 16.4 | 0.08 |
| Esophagus V60Gy [%] | 5.1 | 14.3 | 4.9 | 12.8 | 1.0 | 4.7 | 13.2 | 0.05 * 1 |
1 Although the median value is lower, this parameter was significantly increased with iCE_noBAO compared to CLIN (the value was higher in iCE_noBAO for 16 patients, higher in CLIN for 9 patients and equal for 1 patient).