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. 2021 Nov 15;13(22):5703. doi: 10.3390/cancers13225703

Figure A3.

Figure A3

(A) The apoptosis of MDA-MB231, MDA-MB-468 with downregulation of CTNND1 analyzed by flow cytometry. (B) The colony formation of MDA-MB231, MDA-MB-468 with downregulation of CTNND1. (C) Expression of CTNND1 and CXCR4 in MDA-MB231 and MDA-MB-468 with CTNND1 reduction and PI3K inhibitor LY294002 by qRT-PCR. (D) Immunoblotting of the activation PI3K/AKT/HIF-1α pathway with downregulation of CTNND1 or LY294002 in MDA-MB231 and MDA-MB-468 cells. (E) The enrichment of β-actin in MDA-MB-231 cells transduced with sh-NC or sh-CTNND1 by CHIP-qPCR. All experiments were repeated at least 3 times. *** p < 0.005. Error bars indicate Standard Error of Mean (S.E.M.).