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. 2021 Nov 10;13(22):5620. doi: 10.3390/cancers13225620

Figure 6.

Figure 6

High GSDMD expression associated with IDH wildtype, 1p19q co-deletion and subtypes (A,B) GSDMD expression in glioma tissues with different molecular characteristics. IDH and 1p19q status of glioma in CGGA and TCGA datasets were all downloaded from GlioVis. IDH, isocitrate dehydrogenase. WT, wildtype. Mut, mutant. (C–F) GSDMD expression in different subtypes of GBM was analyzed in CGGA, TCGA, Gravendeel and Rembrandt datasets. CL, Classical; ME, mesenchymal; PN, proneural. (G) IHC staining was used to detect GSDMD expression in glioma tissues (in-house cohort) with different IDH and 1p19q status. * p < 0.05. ** p < 0.01. *** p < 0.001. ns, no significance.