Table 1.
Univariate analysis and multivariate COX analysis of clinical prognostic parameters of all glioma in the TCGA dataset.
| Variables | Univariate Cox Regression | Multivariate Cox Regression | ||
|---|---|---|---|---|
| HR (95%CI) | p Value | HR (95%CI) | p Value | |
| Age (>60 years vs. ≤60 years) | 2.54 (1.77–3.66) | <0.001 | 2.31 (1.62–3.30) | <0.001 |
| Gender (Female vs. male) | 0.94 (0.69–1.30) | 0.72 | - | - |
| WHO Grade (IV vs. I-III) | 0.41 (0.27–0.64) | <0.001 | 0.37 (0.25–0.56) | <0.001 |
| IDH status (wild-type vs. mutant) | 3.99 (2.29–6.95) | <0.001 | 0.43 (0.23–0.82) | 0.01 |
| MGMT promoter (methy vs. unmethy) | 1.31 (0.92–1.88) | 0.13 | - | - |
| Subtypes (ME vs. others) | 0.46 (0.23–0.92) | 0.03 | - | - |
| GSDMA expression | 0.98 (0.92–1.06) | 0.72 | - | - |
| GSDMB expression | 1.12 (0.96–1.31) | 0.17 | - | - |
| GSDMC expression | 0.96 (0.88–1.05) | 0.40 | - | - |
| GSDMD expression | 1.10 (0.92–1.30) | 0.34 | - | - |
| GSDME expression | 1.45 (1.08–1.93) | 0.01 | 1.32 (1.03–1.70) | 0.03 |
| DFNB59 expression | 0.96 (0.88–1.05) | 0.06 | - | - |