Table 2.
Univariate analysis and multivariate COX analysis of clinical prognostic parameters of all glioma in the CGGA dataset.
| Variables | Univariate Cox Regression | Multivariate Cox Regression | ||
|---|---|---|---|---|
| HR (95%CI) | p Value | HR (95%CI) | p Value | |
| Age (>60 years vs. ≤60 years) | 0.96 (0.69–1.33) | 0.81 | - | - |
| Gender (Female vs. male) | 0.98 (0.78–1.23) | 0.78 | - | - |
| WHO Grade (IV vs. I–III) | 3.20 (2.40–4.24) | <0.001 | 3.25 (2.37–4.10) | <0.001 |
| IDH status (wildtype vs. mutant) | 2.47 (1.85–3.30) | <0.001 | 2.32 (1.75–3.08) | <0.001 |
| GSDMA expression | 0.92 (0.74–1.15) | 0.45 | - | - |
| GSDMB expression | 1.01 (0.99–1.03) | 0.56 | - | - |
| GSDMC expression | 0.96 (0.99–1.14) | 0.11 | - | - |
| GSDMD expression | 0.99 (0.99–1.00) | 0.02 | 0.99 (0.99–1.00) | 0.03 |
| GSDME expression | 1.01 (1.00–1.02) | 0.003 | 1.01 (1.00–1.02) | 0.002 |
| DFNB59 expression | 0.99 (0.92–1.06) | 0.76 | - | - |