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A schematic diagram illustrating the effects of short-term and long-term effects of glucocorticoids on mitochondrial function. GR—glucocorticoid receptor; GRE—glucocorticoid responsive element; TF—transcription factors; TREs—transcription factor responsive elements; FKBP51, BAG-1, Hsp-90, Hsp-70, p23—glucocorticoid receptor co-chaperones: FKBP51—FK506 binding protein 5; BAG-1; Co-chaperone 1Hsp-90—heat shock protein 90; Hsp70—heat shock protein 70; p23—co-chaperone protein p23.
