ADC |
antibody–drug conjugate |
BAD |
BCL-2 antagonist of cell death |
BAX |
apoptosis regulator BAX |
BCL-2 |
B-cell CLL/lymphoma 2 |
BCL-XL |
B-cell lymphoma-extra large |
BIM |
BCL-2-like protein 11 |
BRAF |
serine/threonine-protein kinase B-raf |
CAFs |
cancer-associated fibroblasts |
CAM |
cell adhesion molecule |
CC |
colon cancer |
CK2 |
casein kinase 2 |
CMF |
cyclophosphamide/methotrexate/5-fluorouracil chemotherapy |
CRC |
colorectal cancer |
DAG |
diacyloglycerol |
E12/E47 |
immunoglobulin enhancer-binding factor lub transcription factor E2-alpha |
ECM |
extracellular matrix |
EF1/ZEB1 |
elongation factor 1/zinc finger E-box-binding homeobox 1 |
EGF |
epithelial growth factor |
EGFR |
epithelial growth factor receptor |
EMT |
epithelial-to-mesenchymal transition |
ENO1 |
alpha-enolase |
ER |
estrogen receptor |
ERCC1 |
excision repair-cross complementing gene 1 |
ERK |
extracellular signal-regulated kinase |
ESCC |
esophageal squamous cell carcinoma |
FGF |
fibroblast growth factor |
FGFR |
fibroblast growth factor receptor |
FGFRL1 |
fibroblast growth factor receptor-like 1 |
ESCC |
esophageal squamous cell carcinoma |
FLIP |
FLICE-like inhibitory protein |
FOXO1 |
forkhead box protein O1 |
FRA1 |
Fos-related antigen 1 |
FRS2α |
fibroblast growth factor receptor substrate 2 |
GAB1 |
GRB2-associated binding protein 1 |
GC |
gastric cancer |
GIST |
gastrointestinal stromal tumor |
GPCR |
G-protein-coupled receptor |
GRB2 |
growth factor receptor-bound 2 |
GSK3β |
glycogen synthase kinase 3β |
HA |
hyaluronan |
HER2/3 |
receptor tyrosine-protein kinase erbB-2/3 |
HES1 |
hairy and enhancer of split1 |
HCC |
hepatocellular carcinoma |
HGF |
hepatocyte growth factor |
HNC |
head and neck cancer |
HNSCC |
head and neck squamous cell carcinoma |
HO-1 |
hemeoxygenase 1 |
HSC |
hepatic stellate cells |
HSP90 |
heat shock protein 90 |
IP3 |
inositol-1,4,5-triphosphate |
ICC |
intrahepatic cholangiocarcinoma |
IGF |
insulin-like growth factor |
IGFR |
insulin-like growth factor receptor |
IKK-β |
inhibitors of NFκB kinase-β |
JAK |
Janus kinases |
JNK |
c-Jun N-terminal kinase |
KLB |
βKlotho |
LUAC |
lung adenocarcinoma |
mAb |
monoclonal antibody |
MACOM |
MDS1 and EVI1 complex locus protein EVI1 |
MAPK |
mitogen-activated protein kinases |
MCL1 |
myeloid cell leukemia sequence 1 |
MDM2 |
mouse double minute 2 homolog |
MEK |
mitogen-activated protein kinase kinase |
MMTV |
mouse mammary tumor virus |
miRNA |
microRNA |
MRP7 |
multidrug resistance protein 7 |
MT1-MMP |
membrane type 1 matrix metalloproteinase |
mTOR |
mammalian target of rapamycin |
mTORC1/2 |
mammalian target of rapamycin complex 1/2 |
NCT |
neoadjuvant chemotherapy |
NFκB |
nuclear factor-κB |
Notch |
neurogenic locus notch homolog protein |
NRP1 |
neuropilin-1 |
Nrf2 |
nuclear factor E2-related factor 2 |
NSCLC |
non-small-cell lung cancer |
P53 |
cellular tumor antigen p53 |
PARP |
poly (ADP-ribose) polymerase |
PD-ECGF |
platelet-derived endothelial cell growth factor |
PDGFRα |
platelet-derived growth factor receptor α |
P-gp |
P-glycoprotein 1 |
PI3K |
phosphoinositide 3-kinase |
PIP2 |
phosphatidylinositol-4,5-bisphosphate |
PKB |
protein kinase B |
PKC |
protein kinase C |
PLA2G4C |
phospholipase A2γ |
PLCγ |
phospholipase Cγ |
PPHLN1 |
periphilin-1 |
PRKACB |
cAMP-dependent protein kinase catalytic subunit beta |
PUMA |
p53 upregulated modulator of apoptosis |
RAP1 |
RAS-proximate-1 or Ras-related protein 1 |
RAS |
rat sarcoma virus protein |
ROS |
reactive oxygen species |
RTK |
receptor tyrosine kinase |
S6K2 |
ribosomal p70 S6 kinase 2 (jest teżskrót S6K1) |
SCLC |
small cell lung cancer |
SIP1/ZEB2 |
smad interacting protein 1/zinc finger E-box-binding homeobox 2 |
SNT-1 |
suc1-associated neurotrophic factor-induced tyrosine-phosphorylated target |
SOS1 |
son of sevenless 1 |
SOX2 |
Sry-related HMG box 2 |
STAT |
signal transducers and activators of transcription |
TAB |
tumor-associated B cells |
TAC |
taxol, doxorubicin, cyclophosphamide chemotherapy |
TGFβ |
transforming growth factor β |
Tin-PP |
Tin-Protoporphyrin |
TKI |
tyrosine kinase inhibitor |
TSC1/2 |
tuberous sclerosis complex |
TYK2 |
tyrosine kinase 2 |
UPP1 |
uridinephosphorylase 1 |
VEGF |
vascular endothelial growth factor |
VEGFR |
vascular endothelial growth factor receptor |