Table 1.

Examples of resistant cancer types associated with FGF/FGFR.

Cancer Type	Drug	Involved Protein(s)	References
Breast cancer	Etoposide	FGF2	[30]
	5-fluorouracil
	Mifepristone, Telepristone		[50]
	Paclitaxel		[31,33]
	Tamoxifen	FGF1, FGFR2	[48,51]
	Trastuzumab	FGFR4	[49]
		FGF4	[43]
	Lapatinib
Colorectal cancer	5-fluorouracil	FGFR4	[52]
	Irinotecan	FGF2, FGF9	[37]
Liver cancer	Sorafenib	FGF19, FGFR4	[39]
		FGF9	[42]
Head and neck cancer	Paclitaxel	FGF2	[31]
	Cisplatin	FGF2, FGFR2	[35]
	Bevacizumab	FGF2, FGFR3	[53]
Lung cancer	Gefitinib	FGFR1	[54]
	Cisplatin	FGF2	[36]
	Erlotinib	FGFR1	[45]
Bladder cancer	Cisplatin	FGF2	[27]
	Paclitaxel		[31]
Prostate cancer	Paclitaxel	FGF2	[31]
		FGF1, FGF2	[29]
	Doxorubicin
	5-fluorouracil
Blood cancer	Cytarabine	FGF2, FGFR1	[55]
	Etoposide
	Fludarabine	FGF2	[26]
Ovarian and cervical cancer	Paclitaxel	FGF2	[31]
	Etoposide	FGF1	[56]
	Cisplatin		[32]
		FGF13	[38]
Brain cancer	Temozolomide	FGFR1	[57]
		FGF2	[58]
Melanoma	Paclitaxel	FGF2	[34]
	Cisplatin
	Vemurafenib	FGFR3	[47]
Bone cancer	Doxorubicin	FGF2	[28]