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TGF-β signaling pathway drives immune cell exclusion. (A) Active TGF-β signaling pathway drives immune cell exclusion. (B) Inactive TGF-β signaling pathway drives a T cell-inflamed tumor phenotype (adapted from “Cold vs. Hot tumors”, by BioRender.com (2021). Retrieved from https://app.biorender.com/biorender-templates, accessed on 14 October 2021).
