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. 2021 Nov 16;13(22):5723. doi: 10.3390/cancers13225723
ADT Androgen-deprivation therapy
AKT V-akt murine thymoma viral oncogene homolog
ALP Alkaline phosphatase
AR Androgen receptor
ARSIs Androgen receptor signaling inhibitors
AR-V7 AR splice variant 7
BAP Bone-specific alkaline phosphatase
BMM Bone metabolic markers
BSI Bone scan index
cf-DNA Circulating cell-free DNA
CICP C-terminal of type-1 collagen pro-peptide
CPS Combined Positive Score
CSS Cancer-specific survival
CTC Circulating tumor cells
ct-DNA Circulating tumor DNA
CTLA-4 Cytotoxic T-lymphocyte-associated protein 4
CTP C-telopeptide
CYP17A1 Cytochrome P450 17 alpha-hydroxylase/17,20 lyase
DBD DNA-binding domain
DHEA Dehydroepiandrosterone
DHT Dihydrotestosterone
dMMR Mismatch repair deficiency
DNA Deoxyribonucleic acid
dsDNA Double stranded DNA
ESR Erythrocyte sedimentation rate
ERG E26 transformation-specific (ETS)-related gene
FDA Food and Drug Administration
HRR Homologous recombination repair
HSD3B1 3-beta-hydroxysteroid dehydrogenase-1
ICI Immune checkpoint inhibitors
LBD Ligand-binding domain
LDH Lactate dehydrogenase
LHRH Luteinizing hormone-releasing hormone
mCRPC Metastatic castration-resistant prostate cancer
mHSPC Metastatic hormone-naïve/sensitive prostate cancer
MMR Mismatch repair
mRNA Messenger ribonucleic acid
MSI Microsatellite instability
NCI National Cancer Institute
NLR Neutrophil-to-lymphocyte ratio
NTD N-terminal domain
NTx N-telopeptide
ORR Objective response rate
OS Overall survival
P1NP N-terminal propeptide of collagen-1
PARP Poly (ADP-ribose) polymerase
PD-1 Programmed-death receptor-1
PDL-1 Programmed-death ligand-1
PET/CT Positron emission tomography/computed tomography
PFS Progression free survival
PI3K Phosphatidylinositol 3-kinase
PSA Prostate-specific antigen
PSADT PSA doubling time
PSMA Prostate-specific membrane antigen
PTEN Phosphatase and tensin homologue
PYD Pyridinoline
rPFS Radiographic progression free survival
RT-PCR Reverse-transcriptase polymerase chain reaction
SLFN11 Schlafen family member-11 DNA/RNA helicase
SOX9 SRY-related HMG box-9
ssDNA Single-stranded DNA
SUV Standardized uptake value
tALP Total alkaline phosphatase
TMB Tumor mutational burden
68Ga Gallium-68
89Sr Strontium-89
153Sm Samarium-153
177Lu Lutetium-177