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. 2021 Nov 4;10(11):3006. doi: 10.3390/cells10113006

Figure 2.

Figure 2

Dose-dependent transfer of mitochondria from iMSC or ASC to mouse T and B cells in vitro. (A) Representative flow cytometry dot plots showing increased MitoTracker positive CD4+ T, CD8+ T, and B220+ cells in splenocyte-iMSC coculture compared to that of monoculture. (B) Quantification of percent mitochondria transfer to CD4+ T, CD8+ T, and B220+ B cells increased with decreased ratio with both iMSC (upper panel) and ASC (lower panel). Data shown as mean ± SEM from a single experiment repeated independently with similar results (*** p < 0.0001 one-way ANOVA).