Table 2.
Expression of certain studied genes in other cell models as determined by quantitative RT-PCR in unexposed cells. Values are means of four different samples ± standard deviation. a: p < 0.05 for comparison to cN-II+/CD73+ cells as determined by one-way ANOVA test. n.d.: not detected.
| NCI-H292 | RL | |||||
|---|---|---|---|---|---|---|
| Gene | cN-II+/ CD73+ |
cN-II−/ CD73+ |
cN-II+/ CD73− |
cN-II−/ CD73− |
cN-II+ | cN-II− |
| ALOX5AP | 0.6 ± 0.4 | 0.4 ± 0.2 | 0.6 ± 0.1 | 0.5 ± 0.3 | 0.9 ± 0.2 | 1.2 ± 0.3 |
| EMB | 1.4 ± 0.5 | 2.5 ± 0.7 a | 2.4 ± 0.1 a | 2.5 ± 0.5 a | 1.0 ± 0.2 | 1.4 ± 0.1 |
| ENTPD3 | 0.8 ± 0.2 | 1.5 ± 0.5 a | 1.2 ± 0.3 | 1.3 ± 0.5 | n.d. | n.d. |
| LAIR1 | n.d. | n.d. | n.d. | n.d. | 1.5 ± 0.7 | 0.8 ± 0.9 |
| LOX | 1.6 ± 0.8 | 3.17 ± 0.06 a | 2.6 ± 0.3 | 2.7 ± 1.2 | 0.9 ± 0.4 | 0.8 ± 0.4 |
| PLA2G4 | 1.4 ± 0.3 | 1.3 ± 0.2 | 1.4 ± 1.0 | 1.4 ± 0.5 | 0.7 ± 0.6 | 8.0 ± 8.2 |
| ROBO1 | 1.7 ± 1.2 | 2.9 ± 0.7 | 0.7 ± 0.2 a | 0.7 ± 0.2 a | 1.2 ± 0.2 | 0.8 ± 0.1 |
| SERPINA3 | n.d. | n.d. | n.d. | n.d. | n.d. | n.d. |
| SPDEF | 0.8 ± 0.4 | 1.4 ± 0.3 | 1.7 ± 0.7 | 3.3 ± 2.3 a | n.d. | n.d. |