Table 4.

Univariate and multivariate logistic regression analyses of the risk factors associated with CD grade ≥ 2 complications in patients with CRC undergoing a curative resection.

Variables	Univariate			Multivariate
	HR	95% CI	p Value	HR	95% CI	p Value
Age (≥85/<85)	1.771	1.178–2.661	0.006	1.362	0.884–2.098	0.161
Sex (male/female)	1.177	0.827–1.675	0.365
BMI (<22/≥22)	1.345	0.945–1.914	0.1
CCI scores
1–4	1			1
≥5	2.358	1.537–3.617	<0.001	1.601	1.004–2.554	0.048
Albumin (<3.5/≥3.5)	2.767	1.930–3.988	<0.001	1.43	0.890–2.295	0.139
WBC count (≥1000)	1.605	1.030–2.500	0.037	1.011	0.607–1.685	0.966
Hb (<10)	1.207	0.821–1.773	0.339
CEA (≥5)	1.047	0.725–1.513	0.805
PNI (<48)	2.58	1.746–3.811	<0.001	1.184	0.677–2.070	0.554
NLR (≥2.91)	1.911	1.337–2.730	<0.001	1.275	0.832–1.955	0.264
GNRI (<98)	3.088	2.128–4.481	<0.001	1.774	1.035–3.040	0.037
Tumor location
Left/right colon	0.715	0.466–1.097	0.125
Rectum/right colon	0.92	0.602–1.408	0.701
Tumor invasion
T1	1
T2	0.8	0.365–1.753	0.577
T3	0.725	0.378–1.389	0.332
T4	1.263	0.606–2.633	0.533
LN metastasis
N0	1
N1	0.942	0.628–1.414	0.774
N2	1.101	0.661–1.837	0.711
Stage
Stage I	1
Stage II	0.848	0.515–1.397	0.518
Stage III	0.883	0.535–1.458	0.627
Histological grade
Well/moderately differentiated	1
Poorly differentiated	1.262	0.731–2.179	0.403
Histological type
Adenocarcinoma	1
Poor features *	1.606	0.859–3.003	0.138
Operative type (emergency)	3.537	1.417–8.828	0.007	2.177	0.821–5.773	0.118
Operative method (open)	1.123	0.763–1.655	0.556
Neoadjuvant treatment (Yes/No) **	1.156	0.548–2.437	0.704

** For rectal cancer patient only; * Poor features: mucinous/signet ring cell/undifferentiated adenocarcinoma.