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. 2021 Nov 12;13(22):5668. doi: 10.3390/cancers13225668

Table 1.

Gene Ontology analysis of genes differentially regulated upon FEZF1 knock-down.

GO
Cellular Component
Fold
Enrichment
FDR Downregulated Upon
FEZF1 Knock-Down
Upregulated Upon
FEZF1 Knock-Down
growth cone (GO:0030426) 4.99 0.048 UNC5C, CALM3,
FMR1, MAP3K12, STMN3.
HAP1, NGFR, MYH14.
distal axon (GO:0150034) 4.57 0.016 UNC5C, CALM3, RAB5A, FMR1, MAP3K12, SYP, STMN3. BLVRB, HAP1, VAT1, NGFR, MYH14.
axon (GO:0030424) 3.23 0.029 UNC5C, CALM3, SARM1, RAB5A, TENM3, ANK1, FMR1, MAP3K12, SYP, STMN3. BLVRB, HAP1, VAT1, NGFR, MYH14, SEMA6A, ROGDI, SYT2.
transport vesicle membrane (GO:0030658) 4.93 0.036 SREBF1, CALM3, RAB5A, SYP, AFTPH. VAT1, ARFGEF3, CEACAM1, SYT2.
transport vesicle (GO:0030133) 3.65 0.047 SREBF1, CALM3, RAB5A, RAB12, VGF, SYP, AFTPH, SYT2. HAP1, VAT1, ARFGEF3, ROGDI, CEACAM1.