Table 2.
Up- and downregulated miRNAs MF-LCT vs. non-LCT.
| Genes | Log FC | Log CPM | F | p Value | lFDR | Non-LCT | LCT | Status |
|---|---|---|---|---|---|---|---|---|
| hsa-miR-146a-3p | 1.71 | 4.97 | 11.81 | 0.001717 | 0.174221 | 16 | 49 | Up |
| hsa-miR-21-3p | 1.05 | 7.56 | 10.12 | 0.003353 | 0.202974 | 105 | 288 | Up |
| hsa-miR-136-5p | 0.89 | 5.21 | 9.07 | 0.005179 | 0.227844 | 32 | 42 | Up |
| hsa-miR-889 | 0.88 | 6.39 | 8.56 | 0.006415 | 0.242032 | 72 | 96 | Up |
| hsa-miR-539-3p | 0.80 | 3.14 | 8.50 | 0.006581 | 0.243816 | 7 | 10 | Up |
| hsa-miR-708-5p | −1.45 | 8.83 | 12.76 | 0.001194 | 0.163057 | 592 | 290 | Down |
| hsa-miR-744-5p | −0.81 | 7.40 | 11.97 | 0.001618 | 0.172186 | 207 | 122 | Down |
| hsa-miR-3653 | −0.97 | 2.99 | 9.94 | 0.003613 | 0.206878 | 9 | 5 | Down |
| hsa-let-7g-5p | −0.64 | 13.97 | 9.91 | 0.003657 | 0.20753 | 18189 | 13575 | Down |
| hsa-let-7b-5p | −0.71 | 12.52 | 9.17 | 0.004964 | 0.225185 | 7078 | 4459 | Down |
| hsa-miR-664-5p | −0.87 | 3.25 | 8.85 | 0.005685 | 0.233856 | 11 | 7 | Down |
| hsa-miR-5701 | −1.02 | 3.59 | 8.42 | 0.006808 | 0.246205 | 13 | 9 | Down |
Controlling Age, Gender and Stage. p value < 0.01 and fold change > 1.5. FDR: false discovery rate; miR: miRNA; Log FC: log fold change; Log CPM: log counts per million; LCT: large cell transformation.