Table 3.

SARS-CoV-2 anti-spike antibody immunoassay results and S1 memory B cells (MBCs) in CVID patients.

	IgG S1 (OD Ratio)	MBC S + (% of CD24 + CD27 + CD38–Inside CD19 + Cells)	ATM S + (% of CD24–CD27–CD38–CD21–Inside CD19+ Cells)
Baseline, median (IQR)	0.11 (0.08–0.18)	0 (0–0.98)	0 (0–0)
Immunized, median (IQR)	0.30 (0.09–5.39)	0.07 (0–0.13)	0 (0–0.27)
Convalescent, median (IQR)	2.5 (1.07–4.04)	0.16 (0.22)	0 (0–0)
Convalescent/immunized median (IQR)	9.6 (2.75–12.33)	0.25 (1.17–0.31)	0.50 (0.39–1.40)
MoAbs treatment, median (IQR)	6.91 (6.56–9.42)	Nap	Nap

Abbreviations: MBC S+, spike-specific memory B cells; ATM S+, spike-specific atypical memory B cells; Nap, not applicable.