3-MA |
3-Methyladenine |
Abs |
Antibodies |
ACPA |
Anti-Citrullinated Antibodies |
ACR |
American College of Rheumatology |
ADA |
Antidrug Auto-antibodies |
AKT |
Protein Kinase B |
AMPA |
Anti-Modified Protein Antibody |
Anti-CarP |
Antibodies targeting Carbamylated Proteins |
Anti-RA33 |
Antibodies to the heterogeneous nuclear ribonucleoprotein A2/B1 |
APC |
Antigen-Presenting Cell |
APRIL |
Proliferation-Inducing Ligand |
ATG |
Anti-Thymocyte Globulin |
ATP |
Adenosine Triphosphate |
BAFF |
B-cell Activating Factor |
BCR |
B-Cell Receptor |
CCP |
Cyclic Citrullinated Peptide |
CD |
Cluster of Differentiation |
CD4+ CTL |
CD4+ T-cells with Cytotoxic Potential |
CIA |
Collagen Induced Arthritis |
CII |
Collagen type II |
CMV |
Cytomegalovirus |
COX |
Cyclooxygenase |
CQ |
Chloroquine |
CTLA4 |
Cytotoxic T-lymphocyte-associated Protein 4 |
CXCL |
Chemokine Ligand |
DNA |
Deoxyribonucleic Acid |
DAS |
Disease Activity Score |
DMARDs |
Disease-modifying Anti-Rheumatic Drugs |
DNMT |
DNA-Methyltransferase |
EA2 |
Endophilin A2 |
ELISA |
Enzyme Linked Immunosorbent Assay |
EMA |
European Medicines Agency |
EOMES |
Eomesodermin gene |
ER |
Endoplasmic Reticulum |
EULAR |
European League Against Rheumatism |
EV |
Extracellular Vesicle |
FDA |
Food and Drug Administration |
FLS |
Fibroblast-Like Synoviocytes |
FOXP3 |
Forkhead box P3 |
GC |
Glucocorticoid |
GWAS |
Genome Wide Association Studies |
HAT |
Histone Acetyltransferase |
HCQ |
Hydroxy Chloroquine |
HDAC |
Histone Deacetylase |
HLA |
Human Leukocyte Antigen |
HLA-DRB1 |
HLA class II Histocompatibility Antigen DRB1 beta chain |
IFN |
Interferon |
IL |
Interleukin |
JAK |
Janus-Activated Kinase |
LC3-II |
Microtubule-associated proteins 1A/1B light chain 3B |
LTQ-ESI-MS |
Linear ion-trap Electrospray Ionization Mass Spectrometry |
mAb |
Monoclonal Antibody |
MHC II |
Major histocompatibility Complex class II |
MMP |
Matrix-Metallo-Proteinase |
mRNA |
Messenger RNA |
MSC |
Mesenchymal Stem Cell |
mTORC1 |
mTOR complex 1 |
MTX |
Methotrexate |
NADPH |
Nicotinamide Adenine Dinucleotide Phosphate |
NCF1 |
Neutrophil Cytosol Factor 1 |
ncRNA |
Noncoding RNA |
NF-κB |
Nuclear Factor kappa B |
NO |
Nitric Oxide |
NOS2 |
Nitric Oxide Synthase 2 |
NOX2 |
NADPH Oxidase 2 |
NSAID |
Nonsteroidal Anti-Inflammatory Drug |
OA |
Osteoarthritis |
PAD |
Peptidyl Arginine Deiminase |
PBMC |
Peripheral Blood Mononuclear Cell |
PC |
Plasma Cell |
PI3K |
Phosphoinositide 3-Kinase |
Prdm1 |
PR domain Zinc finger protein1 |
PTK |
Protein-Tyrosine-Kinase |
PTPN22 |
Protein tyrosine phosphatase, non-receptor type 22 |
QTL |
Quantitative trait Loci |
RA |
Rheumatoid Arthritis |
RA33 |
Heterogenous nuclear ribonucleoprotein A2/B1 |
RANKL |
Receptor Activator of NF-κB Ligand |
RF |
Rheumatoid Factor |
RNA |
Ribonucleic Acid |
ROS |
Reactive Oxygen Species |
SNP |
Single Nucleotide Polymorphism |
STAT3 |
Signal Transducer and Activator of Transcription 3 |
Syk |
Spleen tyrosine kinase |
TACI |
Transmembrane Activator and CAML Interactor CD Antigen |
TCR |
T-cell Receptor |
Tfh |
Follicular T-helper Cell |
TGF |
Tumor Growth Factor |
Th |
T-helper Cell |
TLR |
Toll-Like Receptor |
TNF |
Tumor Necrosis Factor |
TNFi |
Tumor Necrosis Factor inhibitor |
Treg |
Regulatory T-Cell |
TYK2 |
Tyrosine kinase 2 |