Figure 4. Distinct gene expression patterns of Wnt-3a–regulated genes.

(A) Gene expression pattern 1: Wnt-3a regulates genes in the same direction as the treatments with TGFβ or with siLATS1/2 and combinations thereof. (B) Gene expression pattern 2: Wnt-3a regulates genes in the opposite direction of the other treatments with TGFβ or with siLATS1/2 and combinations thereof. Common target genes of Wnt-3a, siLATS1/2, and TGFβ treatment with corrected P-values of less than 10% were ranked after their absolute log₂ fold change in the Wnt-3a single treatment and filtered for patterns 1 and 2. Log₂ fold changes of the top 30 ranked genes are shown.