Figure S13. Profound changes in gene expression by the combinatorial treatments with TGFβ, siLATS1/2, and Wnt-3a with a global dominance by TGFβ and siLATS1/2.
(A, B, C, D) Volcano plots for differentially regulated genes of the combinatorial treatments with TGFβ, siLATS1/2, and Wnt-3a, as indicated. The dashed vertical lines show the cutoffs for an absolute fold change of 0.5, 1, and 2. The horizontal lines show the cutoffs for a P-value of 0.1, 0.05, and 0.01. The colors correspond to genes with a fold change of greater than 0.5 and a P-value of less than 0.1 (green), greater than 1 and less than 0.05 (blue), and greater than 2 and less than 0.01 (red).