Figure S6. Knockdown of SMAD4, TAZ, YAP, or β-catenin (CTNNB1) does not induce phenotype switching in untreated proliferative melanoma cells.

(A, B) M000921 (A) and M010817 (B) proliferative melanoma cells were transfected with the siSMAD4, siTAZ, siYAP, and siCTNNB1 in the absence of any treatment with other stimuli. Changes in gene expression of the genes which usually change their expression during phenotype switching were assessed by quantitative RT-PCR. Mean + SEM of n = 3 replicates are shown. *P < 0.05; **P < 0.01; ratio-paired t test.