Table 2.
Clinicopathological differences between patients with nonrefractory triple-negative breast cancer and refractory triple-negative breast cancer who could receive surgery with a curative aim.
| No., (%) | Nonrefractory mTNBC | Refractory mTNBC |
|---|---|---|
| Patient, no. | 131 | 207 |
| Neoadjuvant chemotherapy | ||
| Yes | 31 (24) | 130 (63) |
| pCR | 2/31 (6) | 4/130 (3) |
| Grade, histologic | ||
| Well | 5 (4) | 4 (2) |
| Moderate | 40 (31) | 38 (18) |
| Poorly differentiated | 76 (58) | 156 (75) |
| Unknown | 10 (8) | 9 (4) |
| pT stage | ||
| No residual tumor | 2 (2) | 4 (2) |
| 1 | 46 (35) | 55 (27) |
| 2 | 75 (57) | 101 (49) |
| 3 | 8 (6) | 44 (21) |
| 4 | 0 | 3 (1) |
| pN stage | ||
| 0 | 58 (44) | 83 (40) |
| 1 | 41 (31) | 65 (31) |
| 2 | 21 (16) | 30 (14) |
| 3 | 11 (8) | 29 (14) |
Abbreviations: mTNBC, metastatic triple-negative breast cancer; pCR, pathologic complete response; MBC, metastatic breast cancer; pT stage, pathologic tumor stage; pN stage, pathologic nodal stage.