Table 1. Protein constituents of native transient receptor potential melastatin-subfamily member 7 (TRPM7) channels identified by multi-epitope affinity purifications (ME-APs).
| Protein ID | Acc. No.UniProtKB | Name | Primary function | Rel. abundance | |
|---|---|---|---|---|---|
| CL-47 | CL-91 | ||||
| TRPM7 | Q923J1 | TRP channel M7 | Ion channel | = | = |
| CNNM1 | Q0GA42 | Transporter CNNM1, Cyclin-M1 | Potential transporter | << |
|
| CNNM2 | Q5U2P1 | Transporter CNNM1, Cyclin-M2 | Potential transporter | < | << |
| CNNM3 | Q32NY4 | Transporter CNNM1, Cyclin-M3 | Potential transporter | < | << |
| CNNM4 | Q69ZF7 | Transporter CNNM1, Cyclin-M4 | Potential transporter | < | << |
| ARL15 | Q8BGR6 | ADP-ribosylation factor-like protein 15 | Unknown | = | << |
| TP4A1† | Q93096 | Protein tyrosine phosphatase type IVA 1 | Enzyme | <<< | << |
| TP4A3## | Q9D658 | Protein tyrosine phosphatase type IVA 3 | Enzyme |
|
<< |
| TRPM6### | Q9BX84 | TRP channel M6 | Ion channel | <<< | << |
Notes: Relative abundance refers to the amount of TRPM7 as a reference and was classified as follows: = when between 0.33-fold and 3.3-fold of reference, < when between 0.033-fold and 0.33-fold of reference, << when between 0.0033-fold and 0.033-fold of reference, and <<< when less than 0.0033-fold of the reference amount.
Transmembrane proteins; 
cytoplasmic proteins.
†Co-purified from HEK293 cells with anti-M7a (CL-47) and with anti-M7c (CL-91); ##co-purified with anti-M7c from rat brain membranes (CL-91); ###co-purified with anti-M7a from HEK293 cells (CL-47, CL-91).