Table 2.
PERMANOVA results
| Source | Df | Sum Sqs. | Mean Sq. | F Model | Pr(>F) |
|---|---|---|---|---|---|
| Format | 2 | 6.83E+10 | 0.21338 | 96.1452 | 0.001*** |
| Substrate | 2 | 6.06E+10 | 0.18934 | 85.3136 | 0.001*** |
| Status | 1 | 9.46E+09 | 0.02955 | 26.6331 | 0.001*** |
| Project | 5 | 3.23E+10 | 0.10089 | 18.1835 | 0.001*** |
| Segment | 3 | 1.73E+10 | 0.05391 | 16.1951 | 0.001*** |
| Line | 27 | 5.69E+10 | 0.17785 | 5.936 | 0.001*** |
| Treatment | 16 | 6.34E+09 | 0.01979 | 1.1147 | 0.239 |
| Residual | 194 | 6.89E+10 | 0.21528 | ||
| Total | 250 | 3.2012E+11 | 1 |
PERMANOVA output showing the effects of format, substrate, segment (segmental origin of enteroid/colonoid), status (differentiation status), project, line (patient line), and treatment based on Euclidian distances and 999 permutations. Df, degrees of freedom; F model, F statistics; mean sq., mean sum of squares; PERMANOVA, permutational multivariate analysis of variance; Pr (>F), P values; R2, partial R-squared; sums sqs., sum of squares.
***P = 0.001.