Table 1.
Plasma analytes show an enrichment in proteins involved with interleukin signaling after chronic LPS exposure
| Pathway | Reaction Ratio | FDR |
|---|---|---|
| Interleukins signaling | 58/490 | 7.44E-15 |
| Interleukin-4 and -13 signaling | 6/46 | 2.00E-13 |
| Chemokine receptors | 7/19 | 1.02E-08 |
| Interleukin-18 signaling | 4/4 | 3.53E-05 |
| Peptide ligand-binding receptors | 7/76 | 7.03E-05 |
| Interleukin-1 processing | 4/5 | 9.33E-05 |
| Inflammasome pathway | 2/4 | 2.33E-04 |
| Class A/1 (rhodopsin-like receptors) | 7/152 | 0.0038 |
| G Protein-coupled receptor ligand binding | 7/179 | 0.0134 |
| RUNX1 and FOXP3 control of Treg development | 3/20 | 0.0306 |
Pathways are ranked by their false discovery rate (FDR). Reaction ratio, proportion of reactions found vs. total reactions represented by this pathway; LPS, lipopolysaccharides.