Table 3.

List of pathways enriched in CD8⁺ T cells stimulated with IL-4 compared with unstimulated cells using Reactome

Pathway	z-Score	Reaction Ratio	FDR
β-Catenin: T-cell factors-transactivating complex formation	−0.2774	4/43	0.0029
Signaling in response to Wnt	0.6124	44/71	0.0042
Oxidative stress-induced senescence	0.2582	14/40	0.0157
Deactivation of the β-catenin transactivating complex	0.3333	7/14	0.0157
Epigenetic regulation of gene expression	−0.3536	22/34	0.0165
Signaling by RHO GTPases	−0.2887	12/20	0.0165

Pathways are ranked by their false discovery rate (FDR). Z score indicates pathway upregulation or downregulation compared with unstimulated cells. Reaction ratio indicates the proportion of reactions found vs. total reactions represented by this pathway.