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. 2021 Nov 26;19:292. doi: 10.1186/s12916-021-02162-7

Table 3.

Relation of serum metabolome profiles to risk of MetS in young children with maximal adjustment for covariates

Metabolite OR 95% CI p-
Glucose 1.55 (1.25–1.96) 0.0001
Alanine 1.42 (1.16–1.75) 6.8e−4
Tyrosine 1.34 (1.10–1.64) 0.004
Monomethylarginine 1.35 (1.09–1.66) 0.005
Tryptophan 0.79 (0.65–0.96) 0.017
Choline 0.79 (0.64–0.96) 0.023
Deoxy carnitine 1.25 (1.03–1.52) 0.028
Carnitine 1.24 (1.03–1.52) 0.029
Threonine 1.24 (1.02–1.52) 0.031
Lysine 1.23 (1.01–1.50) 0.043
Arginine 1.22 (1.00–1.49) 0.048
Unknown 248.0711 0.82 (0.67–1.00) 0.049
Glutamine/glutamate 0.83 (0.68–1.00) 0.053

OR, odds ratio; CI, confidence intervals; p-, p value for statistical significance

Adjustment for screen time exposure, diet quality score, physical activity, sleep time, maternal social disadvantage index, child’s sex and age (23 (5.0%) missing values; final n numbers: 216 controls and 217 cases)