Table 4.

Associations of fasting serum metabolites to the IDEFICS MetS score in young children

	Adjustment for screen time exposure, diet quality score, physical activity, sleep time, and maternal social disadvantage index				Adjustment for screen time exposure, diet quality score, physical activity, sleep time, maternal social disadvantage index, sex and age
Metabolite	Estimate	SE	z value	p-	Estimate	SE	z value	p-
Glucosea	0.64	0.095	6.70	3.9e−11b	0.65	0.095	6.80	3.50e−11b
Alaninea	0.56	0.097	5.76	1.3e−10b	0.55	0.098	5.62	3.41e−08b
Tyrosinea	0.42	0.098	4.25	2.1e−5b	0.41	0.099	4.16	3.87e−05b
Threoninea	0.35	0.099	3.57	4.2e−4b	0.34	0.10	3.42	0.001
Carnitinea	0.41	0.097	4.17	3.4e−5b	0.41	0.098	4.19	3.35e−05b
Tryptophana	− 0.36	0.099	− 3.59	4.6e−4b	− 0.36	0.099	− 3.62	3.2e−4b
Acetylcarnitine	− 0.42	0.098	− 4.26	3.1e−5b	− 0.42	0.098	− 4.23	2.92e−05b
Hydroxybutyric acids	− 0.38	0.098	− 3.89	2.1e−4b	− 0.39	0.098	− 3.96	8.64e−05b
Methionine	0.34	0.099	3.44	0.001	0.32	0.10	3.24	0.001
Proline	0.32	0.10	3.15	0.002	0.31	0.10	3.06	0.002
Arginine	0.30	0.10	2.95	0.003	0.29	0.10	2.86	0.004
Monomethylargininea	0.29	0.10	2.79	0.006	0.30	0.10	2.85	0.005
Glutamic acid	0.27	0.10	2.72	0.007	0.26	0.10	2.57	0.011
Unknown 129.066	− 0.27	0.10	− 2.62	0.009	− 0.26	0.10	− 2.57	0.011
Glutamine/glutamatea	− 0.25	0.10	− 2.53	0.012	− 0.25	0.10	− 2.44	0.015
Lysinea	0.23	0.10	2.26	0.024	0.22	0.10	2.12	0.035
3-methyl-2-oxovaleric acid	− 0.22	0.099	− 2.26	0.024	− 0.22	0.099	− 2.24	0.026

^aConsistent with adjusted logistic regression analysis

^bp value passed Bonferroni correction p < 0.0008