Table 5.
Prescription of antibiotic and effects on hospitalization period from hospitalized children whom were randomly assigned to a double-blind treatment with either placebo or Bifidobacterium lactis Probio-M8
| Prescription of antibiotic | Placebo | Probio-M8 | P value | Placebo | Probio-M8 | P value | Placebo | Probio-M8 | P value |
|---|---|---|---|---|---|---|---|---|---|
| Admission/baseline | Discharged | 4 weeks after discharged | |||||||
| Overall subjects prescribed with antibiotic | 21.67% | 20.00% | 0.728 | 26.67% | 15.00% | 0.037* | 13.33% | 10.00% | 0.506 |
| LRTI subjects prescribed with antibiotic | 21.67% | 13.33% | 0.094 | 25.00% | 8.33% | 0.001* | 10.00% | 8.33% | 0.621 |
| URTI subjects prescribed with antibiotic | 0.00% | 6.67% | 0.007* | 1.67% | 6.67% | 0.088# | 3.33% | 1.67% | 0.651 |
| Subjects prescribed with antibiotic during admission, and stopped prescription thereafter | 0.00% | 25.00% | < 0.0001* | 69.23% | 83.33% | 0.021* | |||
| New subjects prescribed with antibiotic, but not prescribed during admission | 6.38% | 0.00% | 0.013* | 8.51% | 8.33% | 0.800 | |||
| Patients with antibiotic prescription at admission | Placebo | Probio-M8 | P value | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Hospitalization period (length of stay): | |||||||||
| ≤ 2 days | 69.23% | 58.33% | 0.106 | ||||||
| > 2 days | 30.77% | 41.67% | |||||||
| ≤ 7 days | 92.31% | 100.00% | 0.004* | ||||||
| > 7 days | 7.69% | 0.00% |
*P < 0.05
#P < 0.10