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. Author manuscript; available in PMC: 2022 Dec 1.
Published in final edited form as: Proteins. 2021 Jun 29;89(12):1870–1887. doi: 10.1002/prot.26161

Table 3.

Refinement performance on TS targets

Predictor Mean initial model quality ΔMeasure1
GDT-HA Cα-RMSD [Å] lDDT SphGr GDT-HA Co-RMSD [Å] lDDT SphGr
FEIG-R1 41.89 7.91 55.85% 65.16 +1.17 (52%) −0.04 (43%) +0.71% (54%) −0.04 (40%)
FEIG-R2 44.46 6.48 58.72% 72.21 +2.78 (66%) −0.10 (57%) +1.77% (65%) −0.26 (40%)
FEIG-R3 42.17 7.71 57.11% 68.08 +1.09 (50%) −0.02 (45%) −0.14% (37%) −1.07 (29%)
FEIG-AF 2 74.37 2.44 82.10% 94.11 −6.75 (13%) +0.25 (22%) −6.38% (1%) −2.24 (10%)
1

Mean changes of each measure. Percentage of improved targets are shown in the parentheses.

2

Refinement of AlphaFold2 (group TS427) models. It was performed after the CASP14 conference.