Age (years), mean±SD |
53.3±10.6 |
53.6±10.8 |
52.1±9.9 |
Education |
|
|
|
Less than 12th grade |
257 (8.6) |
235 (10.5) |
22 (2.9) |
High school graduate or equivalent |
789 (26.3) |
660 (29.7) |
129 (16.7) |
Some college |
838 (28.0) |
669 (30.0) |
169 (21.9) |
College graduate |
639 (21.3) |
404 (18.2) |
235 (30.5) |
Post-graduate |
473 (15.8) |
257 (11.6) |
216 (28.0) |
Insurance |
|
|
|
Medicare |
375 (12.6) |
310 (14.0) |
65 (8.4) |
Medicaid |
335 (11.2) |
307 (13.9) |
28 (3.6) |
Private |
1,792 (60.2) |
1,213 (54.9) |
579 (75.3) |
Uninsured |
344 (11.6) |
278 (12.5) |
66 (8.7) |
Other |
132 (4.4) |
101 (45.7) |
31 (4.0) |
Body mass index (kg/m2), mean ± SD |
30.5±7.1 |
31.7±7.0 |
27.1±6.4 |
Body mass index (kg/m2) |
|
|
|
18.5–24.99 |
734 (24.4) |
381 (17.1) |
353 (45.8) |
25.0–29.99 |
836 (27.9) |
628 (28.2) |
208 (27.0) |
30.0–34.99 |
708 (23.6) |
592 (26.6) |
116 (15.0) |
≥35.0 |
720 (24.1) |
626 (28.1) |
94 (12.2) |
History of benign breast disease |
|
|
|
No |
1,055 (35.4) |
1,480 (66.9) |
442 (57.8) |
Yes |
1,922 (64.6) |
733 (33.1) |
322 (42.2) |
Initial mode of breast cancer detection |
|
|
|
Routine mammography |
1,405 (47.1) |
1000 (45.1) |
405 (52.7) |
Clinical breast exam/routine physical exam by healthcare provider |
129 (4.3) |
83 (3.7) |
46 (6.0) |
Self-detection/accidental discovery |
1,034 (34.6) |
794 (35.8) |
240 (31.3) |
Other |
418 (14.0) |
341 (15.4) |
77 (10.0) |
Family history of breast cancer |
|
|
|
No |
2,435 (81.2) |
1,843 (82.7) |
592 (76.8) |
Yes |
563 (18.8) |
384 (17.3) |
179 (23.2) |
Age at menarche (years), mean±SD |
12.5±1.8 |
12.5±1.9 |
12.5±1.5 |
Parity |
|
|
|
Nulliparous |
602 (20.1) |
359 (16.1) |
243 (37.1) |
1–2 |
1,499 (50.0) |
1,139 (51.1) |
360 (54.9) |
≥3 |
897 (29.9) |
729 (32.8) |
52 (8.0) |
History of oral contraceptive use |
|
|
|
No |
1,009 (33.7) |
740 (33.3) |
269 (35.0) |
Yes |
1,984 (66.3) |
1,484 (66.7) |
500 (65.0) |
History of hormone replacement therapy |
|
|
|
No |
2,455 (82.3) |
1,880 (85.0) |
575 (74.6) |
Yes |
528 (17.7) |
332 (15.0) |
196 (25.4) |
|
Tumor clinicopathologic features
|
|
|
|
|
Tumor grade |
|
|
|
Well differentiated |
364 (14.7) |
231 (12.2) |
133 (22.9) |
Moderately differentiated |
1,042 (42.2) |
786 (41.6) |
256 (44.1) |
Poorly differentiated |
1,064 (43.1) |
873 (46.2) |
191 (33.0) |
Tumor size |
|
|
|
<1.0 cm |
1,416 (47.2) |
994 (44.6) |
422 (54.7) |
1.0–2.0 cm |
832 (27.8) |
608 (27.3) |
224 (29.1) |
>2.0 cm |
750 (25.0) |
625 (28.1) |
125 (16.2) |
AJCC stage |
|
|
|
Stage 0 |
497 (18.9) |
362 (18.4) |
135 (20.6) |
Stage I |
1,014 (38.6) |
705 (35.8) |
309 (47.2) |
Stage II |
791 (30.1) |
634 (32.2) |
157 (24.0) |
Stage III |
272 (10.4) |
227 (11.5) |
45 (6.9) |
Stage IV |
52 (2.0) |
43 (2.1) |
9 (1.3) |
ER status |
|
|
|
Positive |
1,985 (73.7) |
1,450 (71.3) |
535 (80.9) |
Negative |
709 (26.3) |
583 (28.7) |
126 (19.1) |
HER2 status |
|
|
|
Positive |
483 (21.0) |
380 (21.6) |
103 (19.0) |
Negative |
1,783 (77.4) |
1,355 (77.0) |
428 (78.8) |
Equivocal |
37 (1.6) |
25 (1.4) |
12 (2.2) |
PR status |
|
|
|
Positive |
1,501 (56.6) |
1,089 (54.1) |
412 (64.4) |
Negative |
1,153 (43.4) |
925 (45.9) |
228 (35.6) |
Lymph node status |
|
|
|
Positive |
737 (31.5) |
589 (32.8) |
148 (27.2) |
Negative |
1,601 (68.5) |
1,206 (67.2) |
395 (72.8) |
Tumor subtype |
|
|
|
Luminal A |
1,311 (58.9) |
955 (55.8) |
365 (69.5) |
HER2-positive |
471 (21.2) |
375 (21.9) |
96 (18.8) |
Triple-negative |
442 (19.9) |
382 (22.3) |
60 (11.7) |