Table 2:
Multivariable Association of Clinical Variables and Change of Vital Signs (Adjusted for Walk Distance) During 6MW Test*.
| Change in O2 saturation | Change in Diastolic blood pressure | Change in Systolic blood pressure | Change in Pulse pressure | |
|---|---|---|---|---|
| Age | NA | −0.12 (−0.19– −0.03) | NA | NA |
| SS genotype | NA | −0.09 (−0.18– −0.001) | NA | NA |
| LDH | NA | NA | −0.10 (−0.21– −0.04) | −0.10 (−0.20 – −0.002) |
| RBC | NA | NA | NA | −0.13 (−0.24– −0.02) |
| TRV | NA | NA | 0.14 (0.04– 0.24) | NA |
| Ejection fraction | 0.10 (0.01–0.19) | NA | −0.09 (−0.20 – −0.001) | NA |
| Absolute reticulocyte count | −0.18 (−0.29– −0.08) | NA | NA | NA |
| BUN | NA | NA | NA | 0.13 (0.03–0.24) |
| Adjusted R2 | 0.04 | 0.02 | 0.02 | 0.03 |
*
Cell represent standardized beta (mean and 95%CI) for change of vital sign per 100 m walk. A negative beta indicates that variable predicts more decrease in vital sign from before to after 6MWT.
For each outcome, predictors that were selected from backward linear regression with a P<0.05.
NA: Not in the model.