Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Aug 26;47(1):180–195. doi: 10.1038/s41386-021-01131-1

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 5 — Top Panels. Whereas retrieving an aversive image during Think trials increased left and right amygdala activity (Green bars), suppressing retrieval on No-Think trials reduced it, more so during intrusions (light blue bars) than non-intrusions (blue bars). A similar though weaker pattern arose for neutral scenes. Bottom Panels. Intrusion-related down-regulations in the amygdala and anterior hippocampus were related to both reduced intrusion frequency and affect suppression (a reduction in perceived negative valence for the suppressed content), according to a behavioral partial least squares (PLS) analysis. Represented here are those voxels significantly associated to the first significant latent variable from PLS, whose downregulation significantly correlated with intrusion proportion for both Negative and Neutral scenes, as well as with affect suppression exclusively for Negative scenes. Error bars indicate bootstrapped 95% CI.