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. 2021 Nov 25;12:6897. doi: 10.1038/s41467-021-27229-0

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© The Author(s) 2021, corrected publication 2021

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Fig. 1 — a Coacervates with surface-confined enzymes and consequent transient asymmetry, leading to autonomous motility of coacervates in the presence of fuel. Schematic that outlines the difference between static (b, c) and dynamic (d, e) structural asymmetry. Static asymmetry with fixed enzyme distribution does not change with time (c), while dynamic asymmetry features a spatiotemporally stochastic enzyme distribution (e). f Stochasticity can be utilized for modulating the motion output via tuning either the life time of the transient asymmetry (enzyme diffusivity) or the organizational states of enzyme distribution (enzyme density).