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. 2021 Nov 25;12:6853. doi: 10.1038/s41467-021-27201-y

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — CP units were profiled for SARS-CoV-2S-specific antibody responses. a Each polar plot depicts an individual donor’s anti-Spike antibody profile, scaled to the minimum and maximum of the 14 CP units profiled. Each wedge represents a SARS-CoV-2 antibody feature, and the size of the wedge indicates the magnitude of the value. The colors represent the feature group: dark blue—antibody isotypes and subclasses; blue—Fc-receptor binding levels; light blue—antibody-dependent functions; light green—neutralizing antibody titer. b Cord diagram representing the statistically significant correlation among S-specific antibody features in CP units with Spearman correlation > 0.5 and two-sided p-value < 0.05. The width of antibody each feature represents the accumulated values of Spearman correlation coefficients of that feature with all other features included in the diagram. The color of the cord represents the strength of Spearman correlation, with a higher correlation having darker red values. Source data are provided as a Source Data file.