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. 2021 Nov 25;4:1325. doi: 10.1038/s42003-021-02859-8

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — a Heatmap depicting the number of possible interactions between the clusters analyzed in preSU and postSU groups. b Heatmap depicting selected cell-cell interactions enriched in postSU group but absent in preSU group. c Circle plot showing upregulation in cellular interaction of cytokine type predicted in iTALK package. d Circle plot showing upregulation in cellular interaction of other type predicted in iTALK package. e Circle plot showing the inferred ACTIVIN signaling networks. f Circle plot showing the inferred BMP signaling networks. g Circle plot showing the inferred TNF signaling networks in postSU group. h Circle plot showing the inferred IFN-γ signaling networks in postSU group.