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. 2021 Nov 15;118(47):e2106115118. doi: 10.1073/pnas.2106115118

Table 1.

 Demographics and reproductive characteristics of the participants in the total sample grouped by mCB status

Demographics Non-CB (n = 251) mCB (n = 71) F (df) P value
Mean SD Mean SD
Maternal age, y 28.46 6.09 25.91 5.2 F(1,320) = 10.28 0.001
Paternal age, y 31.34 7.59 28.08 6.35 F(1,291) = 9.74 0.002
Parity 2.57 1.88 2.89 2.57 F(1,320) = 1.30 0.26
Birthweight, kg 3.25 0.55 3.16 0.65 F(1,266) = 1.21 0.27
Gestational age, wk 38.74 2.71 39.41 1.83 F(1,255) = 3.32 0.07
Placenta weight, g* 658.04 169.85 599.64 113.52 F(1,97) = 2.56 0.001
Prenatal trait anxiety 38.10 10.42 42.94 10.29 F(1,285) = 10.88 <0.001
Prenatal state anxiety 36.76 11.53 42.76 11.28 F(1,284) = 13.76 0.001
Depression 9.08 4.67 11.31 5.51 F(1,301) = 10.97 0.01
N % total N % total Chi-square(df) P value
Child sex (male) 137 54.6 33 46.5 X2(1) = 1.46 0.23
Marital status X2(4) = 20.93 <0.001
 Married 128 51 18 25.4
 Common law 14 5.6 2 2.8
 Single 106 42.3 49 69
 Widowed 0 0 1 1.4
 Divorced/separated 3 1.2 1 1.4
Education X2(6) = 6.5 0.36
 Primary school 6 2.4 3 4.2
 Some high school 25 10 12 16.9
 High school/GED 51 20.3 13 16.3
 Some college 58 23.1 19 26.8
 Associate degree 24 9.6 8 11.3
 Bachelor’s degree 45 17.9 10 14.1
 Graduate degree 42 16.7 6 8.5
Child race X2(4) = 10.03 0.04
 Asian 26 10.4 3 4.2
 Black 48 19.1 18 25.4
 Hispanic 114 45.4 34 47.9
 White 54 21.5 9 12.7
 Other 9 3.6 7 9.9
Prenatal alcohol use 15 6 7 9.9 X2(1) = 1.30 0.25
Prenatal cigarette smoke 14 5.6 19 26.8 X2(1) = 27.13 <0.001
Preeclampsia 15 6 8 11.3 X2(1) = 2.28 0.13
Gestational diabetes 17 6.8 4 5.6 X2(1) = 0.13 0.99
Vaginal infection 13 5.2 3 4.2 X2(1) = 0.11 0.99
C-section 59 23.5 23 32.4 X2(1) = 2.30 0.13

Bold indicates significance. DF, degrees of freedom; GED, General Educational Development test.

*Based on 96 available placenta weights (72 for non-CB and 24 for mCB).

Fisher’s exact test was used due to a small count (<5) in one of the cells.