Fig. 3.

Using AOT as a tool to prevent the motor impairment caused by limb nonuse. The continuous gray line indicates a hypothetical time course of limb motor capabilities before the onset of immobilization. Motor abilities diminish at the time of injury (i.e., immobilization onset) and are represented by dashed lines. The solid red and green lines that begin after immobilization offset indicate the motor recovery of CTRL and AOT groups, respectively. “AOT benefit” indicates the advantage provided by AOT during immobilization in terms of residual motor abilities.