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. 2021 Nov 16;23(1):21. doi: 10.3892/ol.2021.13139

Table I.

Regulators, targets and splicing events of SRSF3.

Regulator Target Splicing event Isoform Cell line (Refs.)
HNRNPL SRSF3 Skipping of exon 4 SRSF3-FL CAL 27 (23)
PTBP1 and PTBP2 OSCC (46)
SLU7 PLC, H358, and HeLa (47)
SRSF3 SRSF3 Inclusion of exon 4 SRSF3-TR K46 (4345)
Amiodarone HeLa (49)
Sodium arsenite HCT116 (50)
circ87MARCA5 U87MG (51)
SRSF3 CDCA5 Retention of intron 1 and2 NA PLC (47)
EIF2B5 Retention of intron 12 EIF2B5-TR SQ20B (16)
PDCD4 Retention of intron 2 Isoform2 SW480 (29)
CD44 Splicing of exons 8, 9, and 10 CD44E HEK293 (32,59)
G6PD Inclusion of exon 12 G6PD-FL HepG2 (54)
GR Inclusion of exon 9a GRα MDA-MB-231 (74,75)
KLF6 Inclusion of exon 3 KLF6-FL Hep3B, Huh7, and HepG2 (22)
MAP4K4 Inclusion of exon 16 Isoform2 and 5 HCT-8 (73)
MDM4 Inclusion of exon 6 MDM4-FL A375 (67)
NUMB Inclusion of exon 12 NUMB-FL MDA-MB-231 (76)
PKM Inclusion of exon 10 PKM2 DLD-1 and WiDr (61)
CASP2 Skipping of exon 9 Casp-2L HeLa and MDA-MB-231 (107)
CLK1 Skipping of exon 4 CLK1-TR WI-38 (40)
FoxM1 Skipping of exon 9 and/or 6 Isoform b and c U2OS and HeLa (24)
HER2 Skipping of exon 16 Δ16HER2 SKBR3 (108)
ELP1 Skipping of exon 20 ELP1-TR HEK293 (40)
ILF3 Skipping of exon 18 or 18b Isoform1 and2 WI-38 (66)
KMT2C Skipping of exon 46a KMT2C-S A2780 (68)
PDK1 Skipping of exon 3a PDK1-TR HEK293 (40)
RAC1 Skipping of exon 3b RAC1b HT29 (33)
SMN2 Skipping of exon 7 SMN2-TR HeLa (83)
MAPT Skipping of exon 10 MAPT-TR SKN-MC and C33A (84)
TP53 Skipping of exon 9i p53β MRC-5 (25)
TP53I3 Skipping of exon 4 TP53I3-TR HEK293 (40)

SRSF3, serine/arginine rich splicing factor 3; NA, not applicable.