Figure 10.

Hypochloremia Is Associated With Exaggerated RV Dysfunction in PAH

(A) Patients with pulmonary arterial hypertension (PAH) with hypochloremia (serum chloride ≤101 mmol/L) have higher right atrial (RA) pressures at every pulmonary vascular resistance (PVR) compared with patients with PAH with normal serum chloride levels (P = 0.0004 between y-intercepts; P = 0.58 between slopes, n = 38 with hypochloremia and n = 162 with normal chloride). (B) Patients with PAH with hypochloremia have a more rapid descent in cardiac output as PVR increases (P = 0.05 between slopes; P = 0.56 between y-intercepts, n = 24 with hypochloremia and n = 131 with normal chloride). Abbreviation in Figure 1.