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. 2021 Nov 22;10(11):2887. doi: 10.3390/foods10112887

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Effect of three krill lipid fractions on cytokine release in RAW264.7 cells with LPS stimulation: (a) TNF-α, (b) IL-1β and (c) IL-6. Blank group referred to the untreated cells; cells treated with LPS alone were considered as the control group. * p < 0.05 versus the control group; the one-way analysis of variance (ANOVA) combined with Games–Howell test was used to analyze the significance. Abbreviations: LPS, lipopolysaccharide; KLF-A, the krill lipid fraction extracted with acetone in the first step; KLF-H, the krill lipid fraction extracted with hexane in the second step; KLF-E, the krill lipid fraction extracted with ethanol in the third step.