Table 2.
Event (number, %) | Any Grade | Grade 3/4 |
---|---|---|
Treatment-related adverse events | 31 (72.1) | 19 (44.2) |
Hypopituitarism | 9 (20.9) | 5 (11.6) |
Maculopapular rash | 7 (16.3) | 0 |
Increased AST | 5 (11.6) | 5 (11.6) |
Increased ALT | 5 (11.6) | 5 (11.6) |
Colitis | 4 (9.3) | 3 (7.0) |
Hypothyroidism | 4 (9.3) | 1 (2.3) |
Pneumonitis | 4 (9.3) | 0 |
Pruritus | 4 (9.3) | 0 |
Arthritis | 3 (7.0) | 2 (3.5) |
Myalgia | 3 (7.0) | 2 (3.5) |
Weight loss | 2 (3.5) | 1 (2.3) |
Hyperglycemia | 1 (2.3) | 1 (2.3) |
Rheumatoid arthritis | 1 (2.3) | 1 (2.3) |
Hyperthyroidism | 1 (2.3) | 0 |
Increased creatinine | 1 (2.3) | 0 |
Urticaria | 1 (2.3) | 0 |
ALT, alanine aminotransferase; AST, aspartate aminotransferase.