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. 2021 Nov 16;10(22):5325. doi: 10.3390/jcm10225325

Table 2.

Adverse events according to immunotherapy.

Event (number, %) Any Grade Grade 3/4
Treatment-related adverse events 31 (72.1) 19 (44.2)
Hypopituitarism 9 (20.9) 5 (11.6)
Maculopapular rash 7 (16.3) 0
Increased AST 5 (11.6) 5 (11.6)
Increased ALT 5 (11.6) 5 (11.6)
Colitis 4 (9.3) 3 (7.0)
Hypothyroidism 4 (9.3) 1 (2.3)
Pneumonitis 4 (9.3) 0
Pruritus 4 (9.3) 0
Arthritis 3 (7.0) 2 (3.5)
Myalgia 3 (7.0) 2 (3.5)
Weight loss 2 (3.5) 1 (2.3)
Hyperglycemia 1 (2.3) 1 (2.3)
Rheumatoid arthritis 1 (2.3) 1 (2.3)
Hyperthyroidism 1 (2.3) 0
Increased creatinine 1 (2.3) 0
Urticaria 1 (2.3) 0

ALT, alanine aminotransferase; AST, aspartate aminotransferase.