Table 1.

The binding mode of each ligand with the different residues inside the active site of SmaR protein.

Ligand	H-Bonding	Hydrophobic Interaction	AutoDock Score
Secnidazole	Arg 50, Tyr 57, Asp 66 69	Ala32, Ala34, Ile 46, Val 68, Leu 69, Trp 81, Thr110, Val 122, Ser 124, Met 126	−5.3
C4-HSL	Arg 50, Trp 53, Asp 66, Thr 110	Val 68, Leu 69, Trp 81, Phe 97, Ala 100, Ile 105, Val 122, Ser 124, Met 126	−6.4