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The effects on apoptosis of free CPI-613 and CPI-613-loaded TTCI NPs at various concentrations. BxPC3 cells were treated with 50 µM CPI-613, 20 µM TTCI NPs and 50 µM TTCI NPs for 48 h and apoptosis was determined by flow cytometry with Annexin V-FITC/PI staining (A). The apoptosis rate (B) following treatment with various therapeutics.
