Table A1.
[18F]-FES uptake in liver metastases per ER status and per PET outcome parameter.
Parameter | ROI Size | ER+ (n = 17) (Median [IQR]) |
ER− (n = 6) (Median [IQR]) |
p-Value |
---|---|---|---|---|
SUVmax | whole-tumor | 11.4 [6.9–12.8] | 7.3 [2.9–11.2] | 0.050 |
SUVmean | whole-tumor | 7.3 [4.4–9.5] | 4.3 [1.6–7.4] | 0.093 |
SUVmin | whole-tumor | 3.9 [2.5–7.7] | 2.2 [1.0–4.1] | 0.141 |
SUVmax | two-thirds | 8.7 [4.6–10.8] | 4.6 [2.0–8.1] | 0.069 |
SUVmean | two-thirds | 6.4 [3.6–9.2] | 3.2 [1.3–5.9] | 0.086 |
SUVmin | two-thirds | 3.9 [2.6–8.3] | 2.2 [1.1–4.8] | 0.123 |
SUVmax | one-third | 6.7 [3.6–9.2] | 3.1 [1.4–5.4] | 0.069 |
SUVmean | one-third | 5.2 [3.2–8.6] | 2.5 [1.2–5.1] | 0.059 |
SUVmin | one-third | 4.9 [2.7–8.3] | 2.2 [1.1–4.9] | 0.080 |
TBRmax | whole-tumor | 0.83 [0.64–1.06] | 0.43 [0.18–0.69] | 0.008 |
TBRmean | whole-tumor | 0.56 [0.38–0.83] | 0.27 [0.10–0.44] | 0.030 |
TBRmin | whole-tumor | 0.30 [0.20–0.69] | 0.14 [0.06–0.25] | 0.050 |
TBRmax | two-thirds | 0.58 [0.40–0.94] | 0.27 [0.12–0.51] | 0.036 |
TBRmean | two-thirds | 0.42 [0.30–0.81] | 0.20 [0.08–0.35] | 0.021 |
TBRmin | two-thirds | 0.30 [0.20–0.74] | 0.14 [0.07–0.29] | 0.069 |
TBRmax | one-third | 0.43 [0.31–0.81] | 0.20 [0.09–0.32] | 0.017 |
TBRmean | one-third | 0.36 [0.28–0.77] | 0.16 [0.08–0.30] | 0.014 |
TBRmin | one-third | 0.32 [0.24–0.74] | 0.14 [0.07–0.29] | 0.030 |
Abbreviations: ER = estrogen receptor; ROI = region-of-interest; IQR = interquartile range; SUV = standardized uptake value; TBR = tumor-to-background ratio.