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. 2021 Nov 15;10(22):5320. doi: 10.3390/jcm10225320

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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(a). The serum concentration of S100A4 in individuals suffering from HS was significantly elevated as compared to controls (p = 0.022). (b). There was statistically significant difference in S100A4 serum concentrations between Hurley stages (p = 0.03), with the highest concentration of S1004 in patients in Hurley II stage. The serum concentrations of S100A4 in patients in Hurley II stage was significantly elevated as compared to controls and individuals with HS in Hurley I stage (p = 0.005, p = 0.012, respectively). The serum concentrations of S100A4 in patients in Hurley III stage was significantly elevated as compared to controls and individuals with HS in Hurley I stage (p = 0.039, p = 0.049, respectively). * is statistically significant result p < 0.05.