Table 2.
Percentage change in the hospital admission rates for congenital malformations, deformations and chromosomal abnormalities from 1999–2019 in England and Wales.
| Diseases | Rate of Diseases in 1999 per 100,000 Persons (95% CI) | Rate of Diseases in 2019 per 100,000 Persons (95% CI) | Percentage Change from 1999–2019 |
|---|---|---|---|
| Congenital malformations of the nervous system | 5.86 (5.65–6.07) |
9.18 (8.93–9.42) |
56.6% |
| Congenital malformations of eye, ear, face and neck | 21.05 (20.65–21.44) |
12.27 (11.99–12.55) |
−41.7% |
| Congenital malformations of the circulatory system | 31.57 (31.09–32.06) |
50.68 (50.11–51.25) |
60.5% |
| Congenital malformations of the respiratory system | 3.67 (3.51–3.84) |
7.39 (7.17–7.60) |
101.1% |
| Cleft lip and cleft palate | 6.77 (6.54–6.99) |
5.90 (5.70–6.10) |
−12.8% |
| Other congenital malformations of the digestive system | 21.05 (20.66–21.44) |
27.78 (27.35–28.20) |
32.0% |
| Congenital malformations of genital organs | 31.28 (30.80–31.76) |
28.52 (28.10–28.95) |
−8.8% |
| Congenital malformations of the urinary system | 11.36 (11.07–11.65) |
11.34 (11.07–11.61) |
−0.2% |
| Congenital malformations and deformations of the musculoskeletal system | 40.34 (39.79–40.88) |
36.98 (36.49–37.47) |
−8.3% |
| Other congenital malformations | 22.97 (22.56–23.39) |
15.80 (15.48–16.12) |
−31.2% |
| Chromosomal abnormalities, not elsewhere classified | 2.82 (2.68–2.96) |
2.71 (2.58–2.84) |
−3.8% |