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The equilibrium dissociation constants between the constructs and HER2 or SAs.
| Affibody Carrier | HER2 (nM) a | HSA (nM) | MSA (nM) |
|---|---|---|---|
| Z-ABD-DM1 | 0.33 ± 0.07 | 0.091 ± 0.005 | 0.279 ± 0.007 |
| ABD-Z-Z-DM1 | 1.33 ± 0.04 | 0.847 ± 0.009 | 0.18 ± 0.03 |
a Each equilibrium dissociation constant (KD value) was measured in triplicates based on the sensorgrams in Supplementary Figure S4.
