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. 2021 Nov 15;22(22):12312. doi: 10.3390/ijms222212312
GIP glucose-dependent insulinotropic polypeptide (previously known as gastric inhibitory peptide)
GLP1 glucagon-like peptide 1
T2D type 2 diabetes
GLP1R glucagon-like peptide 1 receptor
GLP1RA glucagon-like peptide 1 receptor agonist
DPP4 dipeptidyl peptidase 4
DPP4i dipeptidyl peptidase 4 inhibitor
DKD diabetic kidney disease
T1D type 1 diabetes
ESRD end stage renal disease
GRF glomerular filtration rate
KRT kidney replacement therapy
PCSK1 proprotein convertase subtilisin-kexin type 1
PCSK3 proprotein convertase subtilisin-kexin type 3
cAMP cyclic adenosine monophosphate
NEP neutral endopeptidase (neprilysin)
Fc fragment crystallizable
XR extended release
SNAC sodium N-(8-[2-hydroxybenzoyl]amino) caprylate
HbA1c haemoglobin A1c
CVOT cardiovascular outcome trial
LEADER trial the Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results trial
eGFR estimated glomerular filtration rate
SUSTAIN-6 trial the Trial to Evaluate Cardiovascular and Other Long-Term Outcomes with Semaglutide in Subjects with Type 2 Diabetes trial
EXSCEL trial the Exenatide Study of Cardiovascular Event Lowering trial
CARMELINA trial the Cardiovascular and Renal Microvascular Outcome Study with Linagliptin trial
UACR urine albumin-to-creatinine ratio
SAVOR-TIMI 53 trial the Saxagliptin Assessment of Vascular Outcomes Recorded in Patients with Diabetes Mellitus—Thrombosis in Myocardial Infraction trial
AGE advanced glycation end-product
AOPP advanced oxidation protein product
NADPH reduced form of nicotinamide adenine dinucleotide phosphate
NF-ĸB nuclear factor ĸB
TGF-β transformin growth factor-β
ERα oestrogen receptor α
ERβ oestrogen receptor β
GLUT4 glucose transporter type 4
NHE3 sodium-hydrogen exchanger 3
SDF1α stromal cell-derived factor 1α
ICAM1 intercellular adhesion molecule 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TNF tumour necrosis factor
IL-1B interleukin 1B
MAPK8 mitogen-activated protein kinase 8
SOCS3 suppressor of cytokine signalling 3
CCl2 C-C motif chemokine ligand 2
NGAL neutrophil gelatinase-associated lipocalin
CRP C reactive protein
IL-6 interleukin 6
IL-18 interleukin 18
LDL low density lipoprotein
HDL high density lipoprotein