Table 1.
Healthy Volunteers (n = 4) |
HD Patients (n = 24) |
p-Value | |
---|---|---|---|
Age, median (IQR) |
24.50 (23.50, 25.50) | 78.50 (72.75, 84.00) | 0.002 |
Gender, (Male/Female) |
2/2 | 14/10 | 1.00 |
Duration of HD (Year), median (IQR) |
- | 7.50 (3.00, 12.00) | - |
SCr (mg/dL), median (IQR) |
0.66 (0.56, 0.74) | 10.53 (8.95, 12.31) | <0.001 |
BUN (mg/dL), median (IQR) |
10.10 (9.60, 11.10) | 56.65 (45.95, 66.20) | 0.002 |
Albumin (g/dL), median (IQR) |
4.30 (4.25, 4.32) | 3.45 (3.30, 3.80) | 0.002 |
Oxidized albumin ratio (%), median (IQR) |
21.89 (20.05, 24.98) | 47.08 (43.10, 50.95) | 0.002 |
IS (mol/L), median (IQR) |
5.20 (4.75, 6.02) | 118.56 (79.53, 145.57) | <0.001 |
PCS (mol/L), median (IQR) |
10.85 (3.47, 23.06) | 170.02 (110.01, 255.26) | 0.001 |
Arp non-binding rate (%), median (IQR) |
0.64 (0.58, 0.67) | 1.42 (1.19, 2.01) | <0.001 |
HD = hemodialysis, IQR = interquartile range, SCr = serum creatinine, BUN = blood urea nitrogen, IS = indoxyl sulphate, PCS = p-cresyl sulphate.